Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. Some medical conditions may interact with Fosamax. Warning: The facts and figures contained in these reports are accurate to the best of our capability; however, our metrics are only meant to augment your medical knowledge, and should never be used as the sole basis for selecting a new medication. As with any medical decision, be sure to work with your doctor to ensure the best choices are made for your condition. Anon. Raloxifene for postmenopausal osteoporosis. Med Lett Drug Ther.
Other glands. Osteoporosis has also been associated with overactive parathyroid and adrenal glands. Before prescribing medication to suppress or modify cough, it is important to ascertain that the underlying cause of cough is identified, that modification of cough does not increase the risk of clinical or physiological complications, and that appropriate therapy for the primary disease is provided. In young pediatric patients, as well as adults, the respiratory center is sensitive to the depressant action of opioid cough suppressants in a dose-dependent manner. cheapest protopic-ointment online otc
In some cases, spinal fractures can occur even if you haven't fallen. The bones that make up your spine vertebrae can weaken to the point that they may crumple, which can result in back pain, lost height and a hunched forward posture. In: Isselbacher KJ, Braunwald E, Wilson JD et al, eds. In July 2002, the first published results from the Initiative changed all that, he said. What is the most important information I should know about alendronate Binosto, Fosamax? Sex hormones. Lowered sex hormone levels tend to weaken bone. The reduction of estrogen levels in women at menopause is one of the strongest risk factors for developing osteoporosis. Men experience a gradual reduction in testosterone levels as they age. Treatments for prostate cancer that reduce testosterone levels in men and treatments for breast cancer that reduce estrogen levels in women are likely to accelerate bone loss. sumatriptan
For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. Take by as directed. is best absorbed when taken after a meal but may be taken with or without food. Alfacalcidol is usually taken with food. Follow all directions on the product package. Safety and effectiveness of Hycodan in pediatric patients under six have not been established. I'm open to any and everybodies advice. The respiratory depression properties of opioids and their capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury, other intracranial lesions or a pre-existing increase in intracranial pressure. Furthermore, opioids produce adverse reactions which may obscure the clinical course of patients with head injuries.
Maconi G, Porro GB. Multiple ulcerative esophagitis caused by alendronate. Am J Gastroenterol. My OBGYN may NOT be as on top of this as a rheumatologist or osteo doc. Cleveland Clinic: "Temporomandibular Disorders. Because osteoporosis is a chronic condition that requires long-term treatment, it is helpful to have long-term data, Bone explains. Check with your pharmacist about how to dispose of unused medicine. Alendronate increases bone mineral density. Think about how much calcium and vitamin D you normally get in your diet. Caution is advised if you are pregnant or planning to become pregnant in the future. Alendronate may stay in your body for many years. Its effects on an unborn baby are unknown. Discuss the risks and benefits with your doctor before starting treatment with alendronate. For both men and women at increased risk of fracture, the most widely prescribed osteoporosis medications are bisphosphonates. Eating disorders. Severely restricting food intake and being underweight weakens bone in both men and women. Ross PD. Osteoporosis: frequency, consequences, and risk factors. Arch Intern Med. Teriparatide Forteo. This powerful drug is similar to parathyroid hormone and stimulates new bone growth. It's given by daily injection under the skin. After two years of treatment with teriparatide, another osteoporosis drug is taken to maintain the new bone growth. American College of Rheumatology Ad Hoc Committee on Glucocorticoid-induced Osteoporosis. Recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis: 2001 update. Arthritis Rheum. Thacker says. "But if she is, and she's still losing bone mass, we start treatment. It is a long-term commitment. The chances are, you will be on it for a long time. Women who took 5 milligrams daily had smaller gains. Ensrud KE, Black DM, Palermo L et al. Treatment with alendronate prevents fractures in women at highest risk: results for the Fracture Intervention Trial. Arch Int Med.
Good nutrition and regular exercise are essential for keeping your bones healthy throughout your life. Do not consider Communities as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. This drug is available at the lowest co-pay. Do not take this medication at bedtime or while you are still in bed. It may not be absorbed and you may have side effects. Make a note of key personal information, including things like recent life changes, or major stresses. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Talk to your doctor about the use of weight-bearing exercises to help prevent weak bones. Fosamax is available in generic form. GI malabsorption syndrome if necessary. 112 See Metabolic Effects under Cautions. amaryl
Fosamax has been approved by the FDA. D3 in this medication passes into milk. It is unknown if alendronate passes into milk. Consult your doctor before breast-feeding. If you have any questions, ask your doctor or pharmacist. Bisphosphonate labels mention that safety and effectiveness information is based on one to four years -- depending on the drug -- of data, Kehoe said, but optimal length of use is unknown. In patients requiring dental procedures, no data are available to suggest whether discontinuance of therapy prior to procedure reduces the risk of osteonecrosis of the jaw. 112 117 Base management of patients requiring dental treatment on an individual assessment of risks and benefits. Fosamax is the culprit. Merck. Fosamax alendronate sodium tablets patient information. West Point, PA; 1997 Apr. Took first dose this past May and 5 days later had back pain which I attributed to sleeping wrong. Pain continued to worsen. I took the 2nd dose a week later and the pain became unbearable. Affected my entire body and went into my neck and head. Couldn't move without excruciating pain. Ended up in emergency room. Do not take this medication at or while you are still in bed. It may not be absorbed and you may have side effects. Drink at least 2 ounces 60 milliliters of plain water after taking liquid alendronate. Then stay fully upright sitting, standing, or walking for at least 30 minutes and not lie down until after your first food of the day. Alendronate 10 mg once daily in postmenopausal women not receiving HRT. But Actonel works faster, a study by top experts suggests. generic redustat online uk redustat
Swimming, cycling and exercising on machines such as elliptical trainers can provide a good cardiovascular workout, but they're not as helpful for improving bone health. Take your doses of these medications as far as possible from your doses of vitamin D at least 2 hours apart, longer if possible. It may be easiest to take vitamin D at if you are also taking these other medications. Ask your doctor or pharmacist how long you should wait between doses and for help finding a dosing schedule that will work with all your medications. No side effects. With 2nd dose, I developed flu-like symptoms by evening - lasting 24 hrs. When that eased up, I had arthritis-like pain, swelling, heat, redness in forearms, wrists, hands. That lasted about 4 days. That was followed on Day 5 by shooting pain throughout my body that lasted for 3 days. One day with no symptoms and then severe stomach pain started. 8 on a 10 scale. Could hardly walk or move. Felt like my core muscles were affected as every move that would involve core muscles was painful. Pain was mild if I laid perfectly still. Even laughing hurt. It's been a little over 2 weeks and all symptoms seem to have cleared up. I won't be taking this again, and I'm very leary of the other osteoporosis medications now. Way too many people are reporting very severe symptoms just like what I experienced! What are the possible side effects of alendronate Binosto, Fosamax? In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask questions during your appointment at any time that you don't understand something. Merck. Fosamax Plus D alendronate sodium and cholecalciferol tablets prescribing information. Whitehouse Station, NJ; 2011 Jul. Gamble Pharmaceuticals. Actonel risedronate sodium tablets prescribing information. Cincinnati, OH; 2008 Apr. OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Have you noticed a loss of height? Fosamax for the first time. The women were 65 and older.
Soy protein appears to have activity similar to estrogen on bone tissue. Some studies indicate that bone fracture risk is lessened in postmenopausal Asian women who consume higher amounts of soy protein. But soy should be used with caution by women who have a family or personal history of breast cancer. Most available soy products have not been shown to reduce the chance of fractures. Medications, healthy diet and weight-bearing exercise can help prevent bone loss or strengthen already weak bones. Proper dental care is important while you are taking Fosamax. Brush and floss your teeth and visit the dentist regularly. This information should not be used to decide whether or not to take Fosamax or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Fosamax. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Fosamax. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Fosamax. Family history. Having a parent or sibling with osteoporosis puts you at greater risk, especially if your mother or father experienced a hip fracture. Bone HG, Downs RW Jr, Tucci JR et al. for the Alendronate Elderly Osteoporosis Study Centers. Dose-response relationships for alendronate treatment in osteoporotic elderly women. J Clin Endocrinol Metab. This drug is available at a middle level co-pay. Cardwell CR, Abnet CC, Cantwell MM et al. Exposure to oral bisphosphonates and risk of esophageal cancer. JAMA. Fosamax. It may be small consolation for what you have suffered but you have probably saved me untold misery. I am a 58-year-old woman, healthy, and take no medications. Recently I went to a Health Fair Heart Screening and had my heel screened for bone density. The result came back “abnormal”. I went to my Doctor and he referred me for a Bone Mineral Density Test. My hips came backed rated at osteopenia and my back with osteoporosis. Amazingly, my Doctor said “It isn't fair”. He said I was being compared with 30 year old women. Now I know that bone loss is a natural part of the aging process and tends to accelerate after menopause. What the evidence does show is that vitamin D helps the body use to prevent and to build stronger bones, and that vitamin D prevents falls in the elderly by improving muscle function. Do I need a prescription for alendronate? In an editorial published with the study, Wysowski revealed that 34 cases of esophageal cancer associated with bisphosphonate use have now been reported to the FDA. Evaluate patients who present with new thigh or groin pain for possibility of an atypical femoral fracture; include assessment of the contralateral limb. 89 90 91 93 94 Consider interruption of bisphosphonate therapy in patients with manifestations of possible femoral fracture; weigh risks versus benefits of continued treatment. 89 90 Discontinue if a femoral shaft fracture is confirmed. Excessive alcohol consumption. Regular consumption of more than two alcoholic drinks a day increases your risk of osteoporosis. buy cheap toprol mastercard otc toprol
The opinions expressed in WebMD Communities are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. Communities are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Harris ST, Gertz BJ, Genant HK et al. The effect of short term treatment with alendronate on vertebral density and biochemical markers of bone remodeling in early postmenopausal women. J Clin Endocrinol Metab. Safety labeling change and REMS notification. Silver Spring, MD; 2010 Oct 13. From FDA website. The fifth cortisone shot put me in the hospital--must have hit a nerve or done some other damage. Have you experienced any fractures or broken bones? But if you are at high risk and cannot take other medicines, your doctor may recommend it under certain circumstances. If you find it difficult to get enough calcium from your diet, consider taking calcium supplements. However, too much calcium has been linked to kidney stones. Although yet unclear, some experts suggest that too much calcium especially in supplements can increase the risk of heart disease. Our Fosamax Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions. Vitamin D improves your body's ability to absorb calcium and improves bone health in other ways. People can get adequate amounts of vitamin D from sunlight, but this may not be a good source if you live in a high latitude, if you're housebound, or if you regularly use sunscreen or avoid the sun entirely because of the risk of skin cancer. Some of these conditions are risk factors for osteonecrosis. Sedentary lifestyle. People who spend a lot of time sitting have a higher risk of osteoporosis than do those who are more active. Any weight-bearing exercise and activities that promote balance and good posture are beneficial for your bones, but walking, running, jumping, dancing and weightlifting seem particularly helpful. Hosking D, Chilvers CED, Christiansen C et al. Prevention of bone loss with alendronate in postmenopausal women under 60 years of age. N Engl J Med. Who Should Take Forteo? This medication is usually taken once per week unless otherwise directed by your doctor. Choose the day of the week that best fits your schedule and take it on that day each week. purchase pletal usa
Ask your doctor or pharmacist to help select the best product for you. Side Effects List Fosamax Tablet side effects by likelihood and severity. Fleisch H. The use of bisphosphonates in osteoporosis. Br J Clin Pract. Cholecalciferol vitamin D3 in this medication passes into breast milk. It is unknown if alendronate passes into breast milk. Consult your doctor before breast-feeding. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day if you are taking it once a day. If you are taking this medication only once a week, remember to take it on the same day each week. It may help to mark your calendar with a reminder. Fosamax Plus D is to be used only by the patient for whom it is prescribed. Do not share it with other people. Connell MB. Prevention and treatment of osteoporosis in the elderly. Pharmacotherapy. 1999; 19Suppl. Wysowski DK. Reports of esophageal cancer with oral bisphosphonate use. N Engl J Med. Liberman UA, Weiss SR, Bröli J et al. Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. N Engl J Med. The findings probably can be generalized to weekly dosing of Fosamax, he said, but it's unclear how they relate to other bisphosphonates.
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If your symptoms do not improve or if they become worse, check with your doctor. An important note: even if bone density deteriorates during treatment, it is quite likely that the patient would have lost even more bone density without treatment. Race. You're at greatest risk of osteoporosis if you're white or of Asian descent. bloz.info condylox
Wysowski DK, Chang JT. Alendronate and risedronate: reports of severe bone, joint, and muscle pain. Arch Intern Med. That pain may be the only warning. These atypical fractures occur almost by themselves, with little or no reported trauma to the thigh. Lab tests, including bone density and blood calcium levels, may be performed while you use Fosamax. These tests may be used to monitor your condition or check for side effects. Your doctor may also want to evaluate you periodically while you take Fosamax to assess the need to continue treatment. Be sure to keep all doctor and lab appointments.
Your doctor is likely to ask you a number of questions. The FDA convened the meeting because of emerging safety concerns related to long-term use -- generally considered more than three to five years -- of bisphosphonates. Center for Drug Evaluation and Research, Food and Drug Administration. Merck notes in a statement that the Sedghizadeh study contains methodological flaws and that the findings cannot be used to reach "valid scientific conclusions regarding the prevalence of osteonecrosis of the jaw" in patients taking Fosamax. danazol
Some MEDICINES MAY INTERACT with Fosamax. KidsHealth: "Bruxism Teen Grinding or Clenching. Drug Safe, Effective Over Long Haul. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims. Alendronate 5 mg once daily or 35 mg once weekly. travatan